The future of drug development is human. Build it here.
COMPS is the University of Pittsburgh's center for organoids, microphysiological systems, and computational models — the New Approach Methods (NAMs) the FDA and NIH now require. We give investigators the tools, collaborators, and infrastructure to lead.
Human Models.
Human Outcomes.
Built in Pittsburgh.
Mission
COMPS unites expertise in organoids, microphysiological systems, and computational biology to develop, validate, and translate human-relevant model systems for disease research and therapeutic discovery.
Vision
COMPS will establish Pittsburgh as a leading center for New Approach Methodologies (NAMs) by integrating biology, engineering, computation, and clinical translation — connecting patients to the next generation of therapies faster and safer.
Core Capabilities
Organoids
Kidney, cardiac, hepatic, intestinal, and neural iPSC-derived 3D models
Microphysiological Systems
Organ-on-chip, microfluidic platforms, and multi-organ circuits
High-Content Imaging
Spatial transcriptomics, 3D phenotyping, and automated analysis
Computational Modeling
AI toxicology, Digital twins, Multi-scale simulation